Liraglutide and semaglutide are both medications that belong to the same class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. Both drugs are approved by the FDA for the treatment of obesity in adults, and they work by mimicking the action of the hormone GLP-1, which helps regulate blood sugar levels and reduce appetite.
While both drugs are effective for weight loss, there are some advantages of liraglutide over semaglutide that may make it a better choice for certain individuals.
- Dose Titration: Liraglutide dose titration allows you to get to full dose after just 1 month of use compared to semaglutide which often takes 5 months to get to full dose.
- Once-daily dosing: Liraglutide is typically taken once a day, while semaglutide is taken once a week. This may make liraglutide a more convenient option for people concerned about side effects.
- Longer history of use: Liraglutide has been available for a longer period of time than semaglutide, and as a result, there is more long-term safety and efficacy data available for liraglutide.
- Cost: Liraglutide (especially compounded) is significantly less expensive than Wegovy or Ozempic
In summary, liraglutide may have some advantages over semaglutide, such as a lower dose, once-daily dosing, longer history of use, and potentially lower cost. However, the choice between the two medications should be based on individual factors, such as the severity of obesity, medical history, risk of side effects, and cost. It is important to discuss with your Ivím provider which medication may be the best option for you.