Benefits: GLP-1s with Lipotropics and Sermorelin
By: Taylor Kantor, MD Data and Resources from Nature Research, Cennaro et. al, and IVíM Health
Summary: Many people struggle with weight loss as it is commonly more than just diet and exercise that is needed. In fact, scientific studies have shown predetermined weight can have genetic influence as much as 70%. GLP-1 medications target natural pathways to help enhance weight loss results. When combined with other natural therapies like lipotropic injections and sermorelin, weight loss results may be significantly improved. This article discusses the additional benefits lipotropics may provide in improving energy levels, decreasing side effects, and enhancing overall weight loss results as well as how sermorelin may enhance total body sculpting, decrease total body fat percentage, and increase lean muscle mass, even while on a weight loss program.
How Weight Loss Medications Contribute to Success:
When it comes to weight loss, to get optimal results, you have to take a multi-factorial approach. It is estimated that approximately 70% of a patient’s determined weight is based solely on genetics and can often be related to insulin resistance. Weight loss medications target these inherited weight patterns and insulin resistance pathways help to achieve optimal weight loss results with more than 90% of patients achieving success with GLP-1 medications. So why are GLP-1 medications so safe and successful compared to other weight loss medications? The reason is because they mimic a naturally occurring protein in the body called glucagon-like-peptide, a protein responsible for regulating hunger, cravings, and appetite, and also involved in insulin resistance pathways. This also improves the safety of these weight loss medications as only minor changes are made to the natural molecule, allowing it to perform the natural role of GLP-1 in natural pathways. Thus, these medications are also considered as peptide therapies, peptides being natural molecules with minor modifications to exhibit more pronounced effects. When combined with diet and exercise, the average patient loses approximately 15% of total body weight, with approximately ⅓ of patients losing more than 20%. When combined with Ivím’s functional nutrition program and holistic and natural therapies, patient’s achieve even higher rates of success and total overall weight loss.
Benefits of Combining Lipotropic Injections: Energy and Side Effect Reduction
Lipotropic injections, when combined with GLP-1 therapy, may significantly improve energy, sleep, and cognition while also aiding in limiting side effects of the medication and improving overall weight loss results. Lipotropic injections consist of a set of essential nutrients designed at improving the body’s natural metabolic pathways through all natural pathways and are a part of Ivím’s holistic and natural therapies for weight loss and energy improvement. The body requires nutrition and replenishment of essential nutrients, nutrients that are not naturally made by the body but must be absorbed through the diet, to perform various functions, especially in hormone and cellular energy production.
Lipotropic stands for “fat burner” as this set of essential nutrients helps mobilize the release of fats into the bloodstream to utilize for energy production. This results in enhanced fat burning (similar to the effects of ketosis for individuals on ketogenic diets) and the perceived improvement in overall energy levels. At Ivím, lipotropic injections consist of methionine and inositol, B-vitamins, and other amino acids (protein building blocks) and are also commonly called MI-B12 (pronounced “My B12”) injections. Methionine is an amino acid involved in detoxification and fat release from the liver while choline plays a role in fat absorption and metabolism in the liver. B-complex vitamins are widely known for their role in improving energy, sleep, and overall feelings of refreshment. Patients often report enhanced weight loss results, improved energy levels, and better sleep when combining GLP-1 medications with lipotropics.
Benefits of Combining Sermorelin: Body Sculpting and Lean Muscle Mass Retention
Patients taking Sermorelin in combination with GLP-1 medications may experience enhanced weight loss results, improved lean muscle mass, and an overall decrease in total body fat percentage, and it is used in our premier weight loss programs. Sermorelin is an FDA-approved treatment for human Growth Hormone (hGH) deficiency and is commonly used to optimize human Growth Hormone levels in the body. It is also a part of Ivím’s natural and holistic therapies as it occurs as a natural peptide, stimulating the release of hGH through direct effects on the pituitary, a portion of the brain involved in releasing human Growth Hormone. While many hGH therapies are fraught with side effects and adverse effects, because of sermorelin’s natural properties, it has a very limited side effect profile and is a safe therapy for routine use.
As we age, levels of hGH decline over time, with the average patient having hGH levels of less than 50% of baseline by the time they reach their 50’s. Hormone alterations are one of the primary contributors to weight gain and difficulty with weight loss as we age. By supplementing with sermorelin, the goal is to restore hGH levels and the enhanced metabolism that comes with it.
hGH is crucial for growth, development, and regeneration and is commonly used in weight loss, body composition, and anti-aging therapies. The most common reason sermorelin is used is to help enhance body composition, increase lean muscle mass, and decrease total body fat percentage. It is also used to prevent sarcopenia or the loss of lean muscle mass with aging and similarly while on caloric restriction diets and weight loss therapies. Sermorelin is recommended for patients who want to 1) maximize weight loss results 2) improve energy and wakefulness 3) improve overall body composition (increase lean muscle/decrease body fat and 4) exhibit enhanced body sculpting.
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