Compound Medications for Weight Loss
FDA notice on Zepbound®/Mounjaro® shortage: On October 2, 2024, the U.S. Food and Drug Administration determined that the shortage of tirzepatide injection, a glucagon-like peptide 1 (GLP-1) medication, had ended. (Read more)
Schedule a visit with an Ivim provider to discuss what this means for you and your treatment options.
The healthcare landscape, particularly in obesity management, is undergoing a paradigm shift with the emergence of compound medications for weight loss. As patients navigate the loss of insurance coverage and encounter pharmacy shortages, compound medications for weight loss are enabling access for many Americans. Compounded options provide a glimmer of hope for those facing challenges with insurance and the limited availability of brand-name drugs, offering a cost-effective solution that remains accessible through the right providers.
Brand-name drugs like Ozempic®, Wegovy®, Zepbound™, and Mounjaro® can be completely unaffordable without insurance, sometimes exceeding $12,000 annually. Even insured patients are facing challenges, like savings cards expiring and nation-wide prescription fill failures, making compounded alternatives vital for continuous weight management and loss.
What are compounded medications?
Compounding pharmacies offer custom-made medications tailored to individual needs, unlike retail pharmacies that only offer standardized, manufacturer-made medication. They’re required to use pure, pharmaceutical-grade ingredients in FDA-registered facilities and must follow strict industry standards to ensure medication quality and potency. With over 32,000 U.S. pharmacies specializing in compounding, it is a widespread, safe and reputable option for consumers. Going above and beyond, Ivím only works with FDA, NABP, PCAB, and LegitScript certified compounding pharmacies to make sure our patients receive only the highest quality of compound medications.
The growing obesity epidemic makes the role of compound medications even more critical, offering relief for individuals confronting the physical and financial burdens of weight-related health issues. Free from insurance restrictions, overweight and obese individuals are able to access compounded semaglutide and compounded tirzepatide medications based on BMI requirements rather than a diabetes diagnosis. This access ensures a proactive approach to health management.
Addressing the obesity crisis
Recent studies have revealed a troubling trend: obesity now impacts over 41% of the population, a 10% increase from two decades ago. This surge places individuals at greater risk for a range of health complications, including diabetes, heart disease, joint disorders, stroke, and insulin resistance. Heart disease risk escalates due to hypertension, a common comorbidity of obesity, which strains the heart, damages arteries, and increases the incidence of heart attacks and other severe cardiovascular events. Research from Johns Hopkins has highlighted a stark projection: a five-point increase in BMI is linked to a 32% increased risk of heart failure, with predictions suggesting that by 2030, one in five adults may suffer from this condition.
Furthermore, obesity significantly influences the onset of kidney disease by promoting inflammation and oxidative stress, which gradually degrade kidney function. Complicating matters, diabetes exacerbates kidney issues by damaging blood vessels and disrupting waste filtration. Despite diabetes being manageable, it lacks a definitive cure, underscoring the importance of preventative measures, including compounded semaglutide and compounded tirzepatide weight loss medications.
In the realm of reproductive health, obesity’s impact is also profound, with 38-88% of women of childbearing age who have Polycystic Ovary Syndrome (PCOS) being overweight or obese. PCOS can complicate pregnancy efforts and is associated with inflammation, pain, and elevated testosterone levels. Although treatable, like diabetes, PCOS has no cure and can be improved with the help of compounded semaglutide and compounded tirzepatide weight loss medications.
Beyond personal health repercussions, obesity entails substantial economic burdens. On average, adults with obesity incur $1,861 more in annual medical expenses, totaling $172.24 billion nationwide. The financial impact deepens with the need for advanced medical interventions, such as heart surgery, dialysis, and stroke treatment, often required for managing obesity-related conditions. Integrating lifestyle changes with suitable compound weight loss medications offers a viable path to health and hope for individuals battling obesity.
Fortunately, innovative treatments, like compound weight loss medications, are continually emerging. Semaglutide, the active ingredient in Ozempic®and Wegovy®, and tirzepatide, the active ingredient in Zepbound™ and Mounjaro®, are gaining traction as effective options. Notably, the FDA’s recent approval of Zepbound™ for weight loss, has offered greater accessibility and affordability to overweight and obese individuals nationwide.
What’s the difference between semaglutide and tirzepatide?
Both semaglutide and tirzepatide function as GLP-1 receptor agonists, mimicking hormones that enhance insulin secretion and appetite satiety. However, tirzepatide also acts as a dual agonist for glucose-dependent insulinotropic polypeptide (GIP) and GLP-1, offering a combined hormonal action. While both medications are effective, tirzepatide has shown slightly superior weight loss outcomes, with users experiencing an average 20.9% reduction in body weight over 72 weeks, compared to a 15% reduction with semaglutide over 52 weeks. Additionally, tirzepatide tends to have fewer side effects. Compound weight loss medications containing semaglutide and tirzepatide achieve results comparable to their brand-name counterparts, largely due to their same active ingredients.
Conclusion
Compound weight loss medications are carving a path toward a healthier, more equitable future. By embracing innovation, leveraging technology, and championing patient-centered care, we can unlock new frontiers in weight management and usher in a new era of personalized medicine. These medications offer a cost-effective alternative that’s widely available and easily accessible through FDA-registered compounding pharmacies across the country. And it goes beyond weight loss – by reducing obesity in the general population, other risk factors are brought down too. Keeping patients out of hospitals, reducing the risk of chronic disease, and achieving healthy habits for years to come.
With Ivím, you gain the support of our medical experts, ensuring a well-informed and reassuring journey into GLP-1 therapy. Our comprehensive approach combines compound medications with a robust wellness program, including tailored nutrition, exercise plans, educational content, and digital tracking tools, all supported by a vibrant online community. Experience the transformative impact of Ivim’s all-inclusive compound GLP-1 programs, with the added benefits of direct delivery and substantial yearly savings, encapsulating Ivím’s commitment to holistic health and sustainable weight management.
Disclaimer:
Ozempic® and Wegovy® are registered trademarks of Novo Nordisk. Ivim Health has no affiliation with Novo Nordisk. The compound semaglutide products available as part of Ivim Health’s Weight Loss Program are not made by Novo Nordisk or any company affiliated with Novo Nordisk. Zepbound® and Mounjaro® are registered trademarks of Eli Lily. Ivim Health has no affiliation with Eli Lily. The compound tirzepatide products available as part of Ivim Health’s Weight Loss Program are not made by Eli Lily or any company affiliated with Eli Lily.
Compounded drugs do not have FDA-approval. The FDA does not verify the safety, effectiveness, or quality of compounded drugs. The FDA has received adverse event reports after patients used compounded drugs, including compounded semaglutide, a GLP-1 medication mentioned in this article.